History of pharmacopoeia | THE PHARMACOPOEIA OF INDIA | best pharmacy notes downloade

History of pharmacopoeia 


As the drug trade advanced, the requirement for legalised standards to define the character, establish the purity and regulate the strength of medicines was recognised by many civilized nations. the present pharmacopoeias are the result of such recognition.


A pharmacopoeia (Greek Pharmacon, ‘A drug or medicine’ and poeio ‘to make’) is accepted today as a book of standards. A national pharmacopoeia contains an inventory of medication and formulae for medicinal substances/preparations with description, tests for these substances, and therefore the standards, which they need to confirm.


A pharmacopoeia is issued under the authority of the govt. of a rustic. The countries which haven’t developed their pharmacopoeias allow the standards laid down by pharmacopoeias of other countries.


Likewise, if a substance or preparation isn’t included in an exceedingly national pharmacopoeia, the standards laid down in another national pharmacopoeia is also recognised in practice.


Indian pharmacopoeia is that the authorized book of standards in India but other Pharmacopeceias have also been recognised under the Drugs & Cosmetics Act and Rules. far and away the foremost role of pharmacopoeias is within the internal control which facilitates. the regulation of medication trade by the Food and/or Drug Control Administration authority.


Before the appearance of pharmacopoeias, the apothecary had to appear for guidance and knowledge to books written by individuals who had achieved name and fame in medicine.




The history of Indian Pharmacopoeia is as old as that of country Pharmacopoeia. The Bengal Dispensatory was published as early as 1841, The Bengal Pharmacopoeia was published in 1844, nearly 20 years before the publication of the primary BP. As on record, the primary Pharmacopeia of India was published in 1868, which was prepared under the authority of Her Majesty’s Secretary of State for India in

Council was divided into sections on vegetable, animal and that i inorganic medicine and 9 separate sections on products of fermentation and distillation. A supplement Pharmacopoeia of India was published in 1869. it was a list of Indian synonyms of the medicinal plants, products, inorganic and organic substances included within the pharmacopoeia, with explanatory and descriptive remarks, in fourteen Indian languages, additionally to English.


Largely, however, it was the BP, which was considered because the book of standards during the pre-independence era, the primary Indian and Colonial addendum to the BP 1868 was published . in 1901. By the turn of the nineteenth century, the Pharmacopoeia of India ceased to draw attention and passed into oblivion. In 1902 Bose published the ‘Official Indigenous Drugs of India’, which was later published as an enlarged edition in 1932 under the title ‘Pharmacopoeia Indica’.


The ‘Indian Pharmacopceial List’ was published in 1946 by the govt of India, which served as a supplement to British Pharmacopoeia and consisted mainly of crude drugs together with preparations and few synthetics like Urea Stibamine, which were of an Iinterest group to India. The Indian Pharmacopeial Committee was appointed in 1948 to organize a National Pharmacopoeia. the primary edition of the Indian Pharmacopoeia (Pharmacopoeia of India) was published in 1955.


The reconstituted Pharmacopceial Committee compiled a supplement to the primary Edition of the Indian Pharmacopoeia in 1960 to supply standards for a few new drugs introduced into the market. The Second Edition of the Indian Pharmacopoeia was published in }966 te. after a spot of 11 years from the publication of the primary Edition. A supplement to the Second Edition of IP was also published in 1975. The Third Edition of IP appeared in 1985 followed by two addenda in 1989 and 4991,


The fourth edition was published in 1996, the fifth edition in 2007, the sixth edition in 2010 and therefore the seventh edition in 2014. The seventh edition (IP 2014) is presented in four volumes and incorporates 2548 monographs of medication out of which 577 are new monographs consisting of APIs, excipients, dosage forms, antibiotic monographs, insulin products and herbal products etc, Nineteen new Radiopharmaceutical Monographs and one General chapter are first nonce included during this edition.


To ensure that commercial formulations supported by medicinal plants are safe, effective and of ordinary quality, the Regional lab (RRL) Jammu, and therefore the Indian Drugs Manufacturers’ Association (IDMA) Mumbai have jointly published the Indian Herbal Pharmacopoeia in two volumes. Volume 1 published in 1998 contains 20 Monographs and one appendix. Volume II published in 1999 contains


20 monographs and 6 appendices,

To lay down the standards of quality for the drugs of Ayurvedic, Unani and Siddha systems of drugs within the country, the Pharmacopoeial Laboratory for Indian Medicine was established in 1970 at Ghaziabad. The Indian Pharmacopoeial Laboratory could be a modern analytical laboratory capable of doing chemical and microbiological analysis, qualification testing of reference materials and characterization of such reference materials, which become Indian Pharmacopoeia official Reference Materials to be employed in conjunction with the official documentary standards published within the Indian Pharmacopoeia.


The Ministry of Health and Family Welfare, Govt. of India published the primary edition of the Ayurvedic Pharmacopoeia of India in three volumes. Volume I published in 1990 contains 80 monographs and seven appendices of drugs including the allopathic system has been given under the Drugs & Cosmetics Act and Rules.


The discovered standards of Homoeopathic Drugs are released by the Ministry of Health & Family Welfare, Govt. of India m the shape of Homoeopathic Pharmacopoeia of India (HPI). Nine volumes covering standards for 994 drugs and 257 finished products have already been published. HPI is included within the I Schedule of medication & Cosmetics Act, 1940. Recommendatory standards on 257 drugs have also been released and extra 1600 drugs are likely to be included in future.


The Ayurvedic Pharmacopoeia of India is a legal document of standards for the quality of Ayurvedic drugs and substances included ~ therein (under Drugs and Cosmetics Act, 1940). In general, this book is more user friendly for scientists, manufacturers, students, involved in drug quality testing of Ayurvedic medicines, teachers of Dravyaguna, research scholars, physicians of Ayurveda and many others who have an interest in the quality standards of Ayurvedic medicines,


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